Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043972 | 0.70 | ALDH1A1 (0.45) | ALDH1A1RAB9AGAAKDM4ETP53 | |
| SCHEMBL29624840 | 0.70 | AHR (0.64) | AHRHSD11B1ALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL464507 | 0.70 | AHR (0.64) | AHRHSD11B1ALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL8049878 | 0.68 | ALOX5 (0.39) | ALDH1A1HSP90AA1RAB9AGAAKDM4E | |
| SCHEMBL8046545 | 0.67 | ALOX15 (0.33) | ALDH1A1HSP90AA1 | |
| SCHEMBL8043101 | 0.65 | — | — | |
| SCHEMBL13101474 | 0.64 | AHR (0.39) | AHRHSD11B1ALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL4452962 | 0.64 | AHR (0.56) | AHRHSD11B1ALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL8034315 | 0.63 | MMP12 (0.32) | — | |
| SCHEMBL8033667 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |