Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 19/20 | 0.39 |
| ▸ | UBE2M | P61081 | 18/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046035 | 0.86 | HTT (0.41) | — | |
| SCHEMBL8044080 | 0.84 | ALDH1A1 (0.40) | — | |
| SCHEMBL8052603 | 0.83 | DCUN1D1 (0.37) | DCUN1D1UBE2MKDM1A | |
| SCHEMBL8043875 | 0.82 | UBE2M (0.37) | DCUN1D1UBE2M | |
| SCHEMBL8032939 | 0.81 | NPC1 (0.47) | DCUN1D1UBE2M | |
| SCHEMBL8044897 | 0.81 | ALDH1A1 (0.45) | — | |
| SCHEMBL8045080 | 0.80 | LMNA (0.31) | — | |
| SCHEMBL8045829 | 0.78 | HTR7 (0.47) | DCUN1D1UBE2MKDM1A | |
| SCHEMBL8032709 | 0.76 | HTT (0.41) | — | |
| SCHEMBL8717421 | 0.76 | HTR7 (0.36) | DCUN1D1UBE2MKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |
| WO-1998027092-A1 | THIAZOLE COMPOUNDS AND METHODS OF MODULATING SIGNAL TRANSDUCTION | SUGEN, INC. (US) | 1998-06-25 | — | — | WO | disclosed |