Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 16/20 | 0.41 |
| ▸ | PIP4K2C | Q8TBX8 | 14/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044080 | 0.81 | ALDH1A1 (0.40) | HTTALDH1A1LMNAMEN1TP53 | |
| SCHEMBL8051237 | 0.81 | SMN1; SMN2 (0.30) | TSHRSMN1; SMN2 | |
| SCHEMBL8042151 | 0.81 | CYP1A2 (0.37) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL8046035 | 0.79 | HTT (0.41) | HTTALDH1A1LMNAMEN1TP53 | |
| SCHEMBL8046664 | 0.77 | CA12 (0.42) | HTTPIP4K2CALDH1A1PAX8LMNA | |
| SCHEMBL8033751 | 0.77 | RXRA (0.43) | HTTPIP4K2CALDH1A1LMNACA12 | |
| SCHEMBL8042307 | 0.76 | MAPK8 (0.52) | HTTPIP4K2CALDH1A1PAX8LMNA | |
| SCHEMBL8043646 | 0.76 | ALDH1A1 (0.54) | HTTALDH1A1LMNAMEN1TP53 | |
| SCHEMBL8047637 | 0.75 | LMNA (0.39) | HTTPIP4K2CALDH1A1LMNATP53 | |
| SCHEMBL8043814 | 0.75 | NPC1 (0.38) | LMNAMEN1TP53KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |