Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042296 | 0.80 | RAB9A (0.39) | RAB9AALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8032365 | 0.78 | MAPK8 (0.49) | RAB9AALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8049876 | 0.77 | PDK1 (0.52) | RAB9AALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8043683 | 0.76 | HTR1A (0.47) | RAB9AALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8045034 | 0.76 | RAB9A (0.41) | RAB9AALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8044338 | 0.74 | POLB (0.44) | RAB9AALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8050186 | 0.73 | ATP4A (0.35) | RAB9AALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8033941 | 0.72 | SMN1; SMN2 (0.36) | RAB9AALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8045984 | 0.71 | MAPK8 (0.51) | RAB9AALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL10441406 | 0.70 | MAPT (0.38) | RAB9AALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |