Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049983 | 0.93 | RXRA (0.39) | RAB9AKMT2AALDH1A1MAPTF2 | |
| SCHEMBL8045389 | 0.88 | RXRA (0.40) | RAB9AALDH1A1SMN1; SMN2NPC1RXRA | |
| SCHEMBL8046142 | 0.83 | RXRA (0.38) | KMT2AMEN1RXRARXRBRXRG | |
| SCHEMBL8043417 | 0.82 | HDAC6 (0.36) | RAB9ASMN1; SMN2NPC1RXRARXRB | |
| SCHEMBL8043447 | 0.81 | RXRA (0.43) | ALDH1A1RXRARXRBRXRGHCAR2 | |
| SCHEMBL8046313 | 0.81 | ALDH1A1 (0.35) | RAB9AKMT2AALDH1A1MAPTF2 | |
| SCHEMBL8044527 | 0.79 | RAB9A (0.35) | RAB9AKMT2AALDH1A1MAPTF2 | |
| SCHEMBL8033057 | 0.79 | RAB9A (0.44) | RAB9AALDH1A1SMN1; SMN2NPC1RXRA | |
| SCHEMBL8041832 | 0.78 | RAB9A (0.53) | RAB9AKMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8032365 | 0.78 | MAPK8 (0.49) | RAB9AKMT2AALDH1A1MAPTF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |