Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046154 | 0.75 | L3MBTL1 (0.49) | L3MBTL1LMNAMAPK1CASP3SENP7 | |
| SCHEMBL4404236 | 0.73 | EPHX2 (0.52) | EPHX2HSD11B1 | |
| SCHEMBL8046227 | 0.69 | WDR5 (0.58) | L3MBTL1LMNAMAPK1CASP3SENP7 | |
| SCHEMBL4109721 | 0.68 | EPHX2 (0.64) | EPHX2LTA4H | |
| SCHEMBL8211657 | 0.68 | LTA4H (0.60) | L3MBTL1LMNAMAPK1CASP3SENP7 | |
| SCHEMBL11735761 | 0.68 | LTA4H (0.50) | L3MBTL1LMNAMAPK1CASP3SENP7 | |
| SCHEMBL13696728 | 0.67 | LTA4H (0.51) | L3MBTL1LMNAMAPK1CASP3SENP7 | |
| SCHEMBL19808478 | 0.66 | EPHX2 (0.66) | EPHX2HSD11B1L3MBTL1 | |
| SCHEMBL4784023 | 0.66 | RAB9A (0.66) | LMNACASP3SENP7SENP6 | |
| SCHEMBL12875947 | 0.65 | SMN1; SMN2 (0.67) | EPHX2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110944-A | AN ANTIINFLAMMATORY AGENT TREATING INFLAMMATORY BOWEL DISEASE | G. D. SEARLE & CO. (US) | 2000-08-29 | — | — | US | disclosed |