Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 13/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581044 | 0.86 | ALOX15 (0.52) | HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL836697 | 0.84 | ALOX15 (0.50) | HPGDKMT2A | |
| SCHEMBL8046227 | 0.79 | WDR5 (0.58) | L3MBTL1LMNAMAPK1CASP3SENP7 | |
| SCHEMBL8211657 | 0.78 | LTA4H (0.60) | L3MBTL1LMNAMAPK1CASP3SENP7 | |
| SCHEMBL5004504 | 0.75 | ALOX15 (0.70) | L3MBTL1LMNAMAPK1CASP3SENP7 | |
| SCHEMBL28279208 | 0.75 | LMNA (0.46) | L3MBTL1LMNAHPGDKMT2A | |
| SCHEMBL481181 | 0.75 | MAPT (0.46) | L3MBTL1LMNAMAPK1HPGDKMT2A | |
| SCHEMBL1008239 | 0.75 | ATF4 (0.50) | L3MBTL1LMNAHPGDKMT2A | |
| SCHEMBL8046160 | 0.75 | EPHX2 (0.46) | L3MBTL1LMNAMAPK1CASP3SENP7 | |
| SCHEMBL13696728 | 0.74 | LTA4H (0.51) | L3MBTL1LMNAMAPK1CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110944-A | AN ANTIINFLAMMATORY AGENT TREATING INFLAMMATORY BOWEL DISEASE | G. D. SEARLE & CO. (US) | 2000-08-29 | — | — | US | disclosed |