Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033559 | 0.88 | LMNA (0.47) | KMT2AALDH1A1TSHRLMNARAB9A | |
| SCHEMBL8048583 | 0.84 | ALDH1A1 (0.45) | KMT2AALDH1A1TSHRLMNARAB9A | |
| SCHEMBL8032682 | 0.82 | TSHR (0.45) | KMT2AALDH1A1TSHRLMNARAB9A | |
| SCHEMBL8032361 | 0.81 | ALDH1A1 (0.47) | KMT2AALDH1A1LMNARAB9AHTT | |
| SCHEMBL8043945 | 0.80 | ALDH1A1 (0.57) | KMT2AALDH1A1TSHRLMNAHTT | |
| SCHEMBL8032934 | 0.80 | ALDH1A1 (0.50) | KMT2AALDH1A1TSHRLMNARAB9A | |
| SCHEMBL8046147 | 0.80 | ALDH1A1 (0.42) | KMT2AALDH1A1TSHRLMNARAB9A | |
| SCHEMBL8044019 | 0.79 | KMT2A (0.40) | KMT2AALDH1A1LMNARAB9APKM | |
| SCHEMBL31399937 | 0.78 | ALDH1A1 (0.52) | KMT2AALDH1A1TSHRLMNARAB9A | |
| SCHEMBL8043746 | 0.78 | SMN1; SMN2 (0.43) | KMT2AALDH1A1LMNARAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |