SCHEMBL804777

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12177879	0.91	MAPT (0.45)	GPR3MAPTALDH1A1RAB9AHPGD
	SCHEMBL21687080	0.89	GPR3 (0.37)	GPR3MAPTALDH1A1RAB9AHPGD
	SCHEMBL18537972	0.88	GPR3 (0.39)	GPR3MAPTALDH1A1RAB9AHPGD
	SCHEMBL804884	0.88	MAPT (0.39)	GPR3MAPTALDH1A1RAB9AHPGD
	SCHEMBL19777545	0.88	GPR3 (0.34)	GPR3MAPTALDH1A1RAB9AHPGD
	SCHEMBL15096940	0.88	ALDH1A1 (0.36)	GPR3MAPTALDH1A1RAB9AHPGD
	SCHEMBL20277500	0.88	GPR3 (0.44)	GPR3MAPTALDH1A1RAB9AHPGD
	SCHEMBL15276751	0.87	ALDH1A1 (0.35)	GPR3MAPTALDH1A1RAB9AHPGD
	SCHEMBL18086207	0.87	GPR3 (0.40)	GPR3MAPTALDH1A1RAB9AHPGD
	SCHEMBL17307469	0.87	ALOX5 (0.39)	GPR3MAPTALDH1A1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.