Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | HBB | P68871 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048257 | 1.00 | NPC1 (0.59) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL9966009 | 0.87 | MAPT (0.65) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL135604 | 0.87 | MAPT (0.65) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL11055537 | 0.85 | NPC1 (0.48) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL107198 | 0.84 | MAPT (0.61) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL138489 | 0.84 | MAPT (0.61) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1305582 | 0.84 | NFE2L2 (0.74) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1793692 | 0.84 | NFE2L2 (0.74) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL318786 | 0.84 | NFE2L2 (0.74) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1305580 | 0.84 | NFE2L2 (0.74) | NPC1RAB9AMAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3674381-B1 | ORGANIC OPTICAL MATERIAL | JAPAN SCIENCE & TECH AGENCY (JP) | 2023-05-10 | — | — | EP | disclosed |
| EP-3041904-B1 | STYRYL SULFIDE DYES | BASF SE (DE) | 2020-05-20 | — | — | EP | disclosed |
| US-20170189566-A1 | ALPHA-SYNUCLEIN LIGANDS | WASHINGTON UNIVERSITY (US) | 2017-07-06 | — | — | US | disclosed |
| EP-1161555-B1 | 4-(4-HYDROXYSTYRYL)PYRIDINE-CONTAINING SUBSTRATES FOR AN ANALYTE DEPENDENT ENZYME ACTIVATION SYSTEM | PERKINELMER LAS INC (US) | 2008-01-02 | — | — | EP | disclosed |
| US-6020436-A | GRAFT POLYMERIZATION | THE CHROMALINE CORPORATION (US) | 2000-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189566-A1 | ALPHA-SYNUCLEIN LIGANDS | SNCA, PARK7, LRRK2 | NPC1 382/4885RAB9A 152/4885MAPT 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.