Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050210 | 0.86 | HTR1A (0.48) | RAB9ANPC1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL8050615 | 0.75 | ALOX5 (0.35) | KDM4ELTA4HKMT2AMAPTMEN1 | |
| SCHEMBL8709911 | 0.74 | ALOX5 (0.44) | RAB9ANPC1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL4047040 | 0.72 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL8042106 | 0.72 | LTA4H (0.44) | RAB9ANPC1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL8042056 | 0.71 | FBP1 (0.51) | RAB9ANPC1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL8045613 | 0.71 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL8041816 | 0.70 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL8048046 | 0.70 | MAPT (0.47) | RAB9ANPC1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL8050040 | 0.70 | HTT (0.51) | RAB9ANPC1SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |