Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12314020 | 0.91 | TTR (0.31) | — | |
| SCHEMBL80414 | 0.91 | TTR (0.31) | — | |
| SCHEMBL10101118 | 0.89 | APP (0.32) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1108147 | 0.81 | APP (0.33) | CYP19A1MAOAMAOB | |
| SCHEMBL16219560 | 0.81 | ALDH1A1 (0.30) | ALDH1A1MAPT | |
| SCHEMBL28789994 | 0.80 | MCL1 (0.40) | MCL1KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL1108163 | 0.80 | NFE2L2 (0.31) | KDM4EMAPT | |
| SCHEMBL12160640 | 0.80 | NFE2L2 (0.31) | KDM4EMAPT | |
| SCHEMBL12391465 | 0.80 | APP (0.30) | — | |
| SCHEMBL10101114 | 0.80 | APP (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029796-B2 | Fluorescent probes for silver ION detection | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2024-07-09 | — | — | US | disclosed |
| US-9919995-B2 | Photoactivatable caged compounds with AIE characteristics: method of preparation and applications | Tang, Benzhong (CN) | 2018-03-20 | — | — | US | disclosed |
| US-9618453-B2 | Aggregation induced emission of fluorescent bioprobes and methods of using the same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-04-11 | — | — | US | disclosed |
| US-20160299078-A1 | Specific Detection and Quantification of Cardiolipin and Isolated Mitochondria by Positively Charged AIE Fluorogens and Method of Manufacturing Thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-10-13 | — | — | US | disclosed |
| US-9315465-B2 | Photostable AIE luminogens for specific mitochondrial imaging and its method of manufacturing thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-04-19 | — | — | US | disclosed |
| US-9279806-B2 | Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-03-08 | — | — | US | disclosed |
| US-9228949-B2 | Aggregation-induced emission luminogens for metal ion detection | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-01-05 | — | — | US | disclosed |
| US-20150376112-A1 | Photoactivatable Caged Compounds with AIE Characteristics: Method of Preparation and Applications | TANG, BENZHONG (HK) | 2015-12-31 | — | — | US | disclosed |
| US-20150031607-A1 | WATER-SOLUBLE AIE LUMINOGENS FOR MONITORING AND RETARDATION OF FIBRILLATION OF AMYLOID PROTEINS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-01-29 | — | — | US | disclosed |
| US-20140212359-A1 | PHOTOSTABLE AIE LUMINOGENS FOR SPECIFIC MITOCHONDRIAL IMAGING AND ITS METHOD OF MANUFACTURING THEREOF | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2014-07-31 | — | — | US | disclosed |
| US-8679738-B2 | Water-soluble AIE luminogen for monitoring and retardation of amyloid fibrillation of insulin | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2014-03-25 | — | — | US | disclosed |
| US-20130266953-A1 | AGGREGATION INDUCED EMISSION OF FLUORESCENT BIOPROBES AND METHODS OF USING THE SAME | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2013-10-10 | — | — | US | disclosed |
| US-20130059392-A1 | AGGREGATION-INDUCED EMISSION LUMINOGENS FOR METAL ION DETECTION | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2013-03-07 | — | — | US | disclosed |
| US-8263018-B2 | Detecting aggregation-induced emission via fluorescence | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2012-09-11 | — | — | US | disclosed |
| US-20120172296-A1 | WATER-SOLUBLE AIE LUMINOGEN FOR MONITORING AND RETARDATION OF AMYLOID FIBRILLATION OF INSULIN | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2012-07-05 | — | — | US | disclosed |
| US-8129111-B2 | Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2012-03-06 | — | — | US | disclosed |
| US-7939613-B2 | Probes/sensors for biomacromolecules; films; cosmetics | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2011-05-10 | — | — | US | disclosed |
| US-20100009362-A1 | Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-01-14 | — | — | US | disclosed |
| US-20080220407-A1 | Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140212359-A1 | PHOTOSTABLE AIE LUMINOGENS FOR SPECIFIC MITOCHONDRIAL IMAGING AND ITS METHOD OF MANUFACTURING THEREOF | MAVS, AIFM1, GSR | MCL1 250/4885KDM4E 2210/4885ALDH1A1 4054/4885 |
| US-20150376112-A1 | Photoactivatable Caged Compounds with AIE Characteristics: Method of Preparation and Applications | TYR, S100A9, CENPE | MCL1 1151/4885KDM4E 123/4885ALDH1A1 2112/4885 |
| US-20130059392-A1 | AGGREGATION-INDUCED EMISSION LUMINOGENS FOR METAL ION DETECTION | PARN, IK, PARG | MCL1 474/4885KDM4E 2151/4885ALDH1A1 2125/4885 |
| US-20120172296-A1 | WATER-SOLUBLE AIE LUMINOGEN FOR MONITORING AND RETARDATION OF AMYLOID FIBRILLATION OF INSULIN | IAPP, IGF2BP1, IGF2BP2 | MCL1 650/4885KDM4E 4534/4885ALDH1A1 3002/4885 |
| US-20080220407-A1 | Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | FUS, CD63, EPCAM | MCL1 925/4885KDM4E 4884/4885ALDH1A1 1173/4885 |
| US-12029796-B2 | Fluorescent probes for silver ION detection | FUS, APC, ALB | MCL1 106/4885KDM4E 4720/4885ALDH1A1 899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.