Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12808921 | 0.78 | ADH1B (0.34) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL3870221 | 0.78 | FPR3 (0.36) | SMN1; SMN2ADH1BADH1CADH1AADH7 | |
| SCHEMBL2259175 | 0.77 | TRPM5 (0.43) | TRPM5SLC6A3RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2710573 | 0.76 | — | — | |
| SCHEMBL13680962 | 0.76 | SLC6A3 (0.40) | TRPM5SLC6A3RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL933968 | 0.75 | — | — | |
| SCHEMBL27377539 | 0.74 | TRPM5 (0.41) | TRPM5SLC6A3RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4211476 | 0.74 | CDC7 (0.49) | RAB9ASMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL4664006 | 0.73 | NPSR1 (0.44) | TRPM5SLC6A3RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL13142433 | 0.71 | NOS1 (0.48) | TRPM5SLC6A3RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563901-B2 | Intermediates of 2-substituted carbapenem derivatives and process for production thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-07-21 | — | — | US | disclosed |
| US-7524951-B2 | Intermediates of 2-substituted carbapenem derivatives and process for production thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| US-20090082571-A1 | Intermediates of 2-substituted carbapenem derivatives and process for production thereof | SASAKI TOSHIRO | 2009-03-26 | — | — | US | disclosed |
| US-20080167475-A1 | Intermediates of 2-substituted carbapenem derivatives and process for production thereof | SASAKI TOSHIRO | 2008-07-10 | — | — | US | disclosed |
| US-20080076917-A1 | Intermediates of 2-Substituted Carbapenem Derivatives and Process for Production Thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 2008-03-27 | — | — | US | disclosed |
| EP-0669336-B1 | NOVEL CEPHEM DERIVATIVES | MEIJI SEIKA CO (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5663162-A | BACTERICIDES AND ANTIBIOTICS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0669336-A1 | NOVEL CEPHEM DERIVATIVE | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167475-A1 | Intermediates of 2-substituted carbapenem derivatives and process for production thereof | MGAM, G6PD, COASY | TRPM5 3728/4885SLC6A3 4656/4885RAB9A 2104/4885 |
| US-20080076917-A1 | Intermediates of 2-Substituted Carbapenem Derivatives and Process for Production Thereof | MGAM, G6PD, COASY | TRPM5 3728/4885SLC6A3 4656/4885RAB9A 2104/4885 |
| US-20090082571-A1 | Intermediates of 2-substituted carbapenem derivatives and process for production thereof | MGAM, G6PD, COASY | TRPM5 3728/4885SLC6A3 4656/4885RAB9A 2104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.