Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.57 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.57 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25139837 | 0.87 | MAPT (0.66) | PLOD2PLOD3PLOD1CYP1A2CYP3A4 | |
| Ethyl 4-Pyridylketone SCHEMBL31726137 | 0.85 | PLOD2 (0.52) | PLOD2PLOD3PLOD1CYP1A2CYP3A4 | |
| Propiophenone SCHEMBL28271870 | 0.83 | L3MBTL1 (0.60) | PLOD2PLOD3PLOD1CYP1A2CYP3A4 | |
| SCHEMBL19076171 | 0.82 | HDAC1 (0.59) | PLOD2PLOD3PLOD1CYP1A2CYP3A4 | |
| Propyl 4-Pyridyl Ketone SCHEMBL4952700 | 0.82 | HSD17B3 (0.61) | PLOD2PLOD3PLOD1CYP1A2CYP3A4 | |
| SCHEMBL8051337 | 0.82 | SMN1; SMN2 (0.70) | ALDH1A1HPGDL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL15988710 | 0.80 | CYP2C19 (0.61) | PLOD2PLOD3PLOD1CYP1A2CYP3A4 | |
| SCHEMBL10948430 | 0.80 | PLOD2 (0.83) | PLOD2PLOD3PLOD1CYP1A2CYP3A4 | |
| SCHEMBL5473602 | 0.80 | KDM4E (0.73) | ALDH1A1L3MBTL1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7220547 | 0.79 | HSD17B3 (0.63) | PLOD2PLOD3PLOD1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 365 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915149-B1 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | AETERNA ZENTARIS GMBH (DE) | 2018-10-10 | — | — | EP | claimed |
| CN-106317073-B | A kind of α of lavo-ofloxacin, alpha, beta-unsaturated ketone derivative and its preparation method and application | HENAN UNIVERSITY (CN) | 2018-08-31 | — | — | CN | claimed |
| CN-106317083-B | A kind of α of Rufloxacin, alpha, beta-unsaturated ketone derivative and its preparation method and application | 河南大学 | 2018-08-31 | — | — | CN | claimed |
| CN-106317074-B | A kind of α of Ofloxacin, alpha, beta-unsaturated ketone derivative and its preparation method and application | HENAN UNIVERSITY (CN) | 2018-08-31 | — | — | CN | claimed |
| CN-106317054-B | A kind of α of Enoxacin, alpha, beta-unsaturated ketone derivative and its preparation method and application | 河南大学 | 2018-07-31 | — | — | CN | claimed |
| CN-106277159-A | A kind of methylene blue and the processing method of Congo red organic pollution | 渤海大学 | 2017-01-04 | — | — | CN | claimed |
| EP-1691610-B1 | METHOD FOR MODIFYING THE BEHAVIOUR OF THRIPS WITH PYRIDINE DERIVATIVES | NZ INST PLANT & FOOD RES LTD (NZ) | 2016-03-09 | — | — | EP | claimed |
| US-8962003-B2 | Insect behaviour modifying compounds | THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED (NZ) | 2015-02-24 | — | — | US | claimed |
| US-8710089-B2 | Triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors | ZENTARIS GMBH (DE) | 2014-04-29 | — | — | US | claimed |
| US-20100331343-A1 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | ZENTARIS GMBH (DE) | 2010-12-30 | — | — | US | claimed |
| US-20080241205-A1 | Insect Behaviour Modifying Compounds | THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED (NZ) | 2008-10-02 | — | — | US | claimed |
| WO-2008098977-A1 | NOVEL TRIAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS | ÆTERNA ZENTARIS GMBH (DE) | 2008-08-21 | — | — | WO | claimed |
| EP-1958631-A1 | Novel triazole derivatives as ligands of G-protein coupled receptors | AEterna Zentaris GmbH (DE) | 2008-08-20 | — | — | EP | claimed |
| EP-1915149-A2 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | AEterna Zentaris GmbH (DE) | 2008-04-30 | — | — | EP | claimed |
| US-20070208061-A2 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | ZENTARIS GMBH (DE) | 2007-09-06 | — | — | US | claimed |
| EP-1757290-A1 | Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors | Zentaris GmbH (DE) | 2007-02-28 | — | — | EP | claimed |
| WO-2007020013-A2 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | ÆTERNA ZENTARIS GMBH (DE) | 2007-02-22 | — | — | WO | claimed |
| US-20070037857-A1 | Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors | ZENTARIS GMBH (DE) | 2007-02-15 | — | — | US | claimed |
| EP-1691610-A1 | INSECT BEHAVIOUR MODIFYING COMPOUNDS | New Zealand Institute for Crop & Food Research Limited and Plant Research International B.V. (NL) | 2006-08-23 | — | — | EP | claimed |
| WO-2005046330-A1 | INSECT BEHAVIOUR MODIFYING COMPOUNDS | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2005-05-26 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208061-A2 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | GIPR, GHSR, GPR119 | PLOD2 2569/4885PLOD3 793/4885PLOD1 2791/4885 |
| US-20100331343-A1 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | GIPR, GHSR, GPR119 | PLOD2 2569/4885PLOD3 793/4885PLOD1 2791/4885 |
| US-20080241205-A1 | Insect Behaviour Modifying Compounds | PNMT, ACHE, THOP1 | PLOD2 3342/4885PLOD3 3482/4885PLOD1 4247/4885 |
| US-20070037857-A1 | Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors | GIPR, GHSR, GPR119 | PLOD2 2569/4885PLOD3 793/4885PLOD1 2791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.