Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 12/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071910 | 0.94 | ACHE (0.53) | ACHEBCHEMAOBSLC6A2SLC6A4 | |
| Trifluoroacetic Acid SCHEMBL8067000 | 0.87 | XDH (0.44) | SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL8066735 | 0.86 | MAOA (0.45) | SIGMAR1MAOA | |
| SCHEMBL7831263 | 0.84 | ACHE (0.52) | ACHEBCHEMAOBMAOA | |
| SCHEMBL8057465 | 0.82 | ACHE (0.46) | ACHEBCHEMAOBSLC6A2SLC6A4 | |
| SCHEMBL7827131 | 0.79 | PARP1 (0.50) | ACHEBCHEMAOBSIGMAR1MAOA | |
| SCHEMBL8068050 | 0.79 | XDH (0.48) | SIGMAR1MAOA | |
| SCHEMBL8067124 | 0.78 | MAOA (0.52) | ACHESLC6A4SIGMAR1MAOA | |
| SCHEMBL7816229 | 0.77 | MAOA (0.47) | MAOBMAOA | |
| SCHEMBL7827564 | 0.76 | MAOA (0.47) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |