Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8067000 | 0.92 | XDH (0.44) | XDHSIGMAR1DRD3HRH3HRH4 | |
| SCHEMBL7827131 | 0.92 | PARP1 (0.50) | XDHSIGMAR1HRH3MAOAPARP1 | |
| SCHEMBL8067124 | 0.90 | MAOA (0.52) | SIGMAR1HRH3MAOAPARP1KDM4E | |
| SCHEMBL7831263 | 0.88 | ACHE (0.52) | HRH3MAOAKDM4E | |
| SCHEMBL8071910 | 0.84 | ACHE (0.53) | SIGMAR1HRH3MAOA | |
| Trifluoroacetic Acid SCHEMBL8066735 | 0.84 | MAOA (0.45) | SIGMAR1HRH3MAOAPARP1KDM4E | |
| SCHEMBL7826517 | 0.82 | MAOA (0.52) | MAOAPARP1KDM4E | |
| SCHEMBL7826175 | 0.82 | MAOA (0.54) | SIGMAR1DRD3HRH3MAOAPARP1 | |
| SCHEMBL7824605 | 0.81 | CTSV (0.43) | MAOA | |
| SCHEMBL7827211 | 0.81 | HSD17B10 (0.51) | PARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114431-A | Plastic composition | GRIFFIN CORP. (US) | 2000-09-05 | — | — | US | claimed |
| CN-100558356-C | The method that using cyclooxygenase-2-inhibitor 2 treatment and prophylaxis of tumours form | G D SIORL & CO (US) | 2009-11-11 | — | — | CN | disclosed |
| CN-1332661-C | Methods of treating and preventing neoplasia using cyclooxygenase-2 inhibitors | SEARLE & CO (US) | 2007-08-22 | — | — | CN | disclosed |
| CN-1660083-A | Method of using benzenesulphoamides that are cyclooxygenase-2-inhibitors in the treatment and prevention of neoplasia | G D SIORL & CO (US) | 2005-08-31 | — | — | CN | disclosed |
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| CN-1247470-A | Methods of using cyclooxygenase-2 inhibitors as anti-angiogenic agents | SEARLE & CO (US) | 2000-03-15 | — | — | CN | disclosed |
| CN-1244122-A | Methods of treating and preventing neoplasia using cyclooxygenase-2 inhibitors | SEARLE & CO (US) | 2000-02-09 | — | — | CN | disclosed |
| EP-0422204-A1 | PLASTIC CRAYON | BINNEY & SMITH INC. (US) | 1991-04-17 | — | — | EP | disclosed |
| WO-1990012845-A1 | PLASTIC CRAYON | BINNEY & SMITH INC. (US) | 1990-11-01 | — | — | WO | disclosed |