Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 0.47 |
| ▸ | CTSV | O60911 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 10/20 | 0.44 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827564 | 0.97 | MAOA (0.47) | MAOACTSVCTSLMAOBRHEB | |
| SCHEMBL7824605 | 0.90 | CTSV (0.43) | MAOACTSVCTSL | |
| SCHEMBL7829082 | 0.89 | CTSV (0.44) | MAOACTSVCTSL | |
| SCHEMBL7824749 | 0.88 | CTSV (0.60) | MAOACTSVCTSLMAOB | |
| SCHEMBL7832144 | 0.85 | CTSV (0.42) | MAOACTSVCTSL | |
| SCHEMBL7831263 | 0.85 | ACHE (0.52) | MAOAMAOB | |
| SCHEMBL7823832 | 0.84 | CTSV (0.41) | MAOACTSVCTSL | |
| SCHEMBL7826517 | 0.83 | MAOA (0.52) | MAOACTSVCTSL | |
| SCHEMBL8073544 | 0.82 | RUVBL1 (0.54) | — | |
| SCHEMBL7826175 | 0.82 | MAOA (0.54) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |