Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046670 | 0.85 | KCNA5 (0.39) | SMN1; SMN2HTTALPLALPIALPG | |
| SCHEMBL8059121 | 0.85 | FDPS (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A | |
| SCHEMBL7644315 | 0.79 | GRM2 (0.44) | SMN1; SMN2RAB9AMAPTTDP1 | |
| SCHEMBL8059183 | 0.79 | CYP1A2 (0.47) | SMN1; SMN2CYP1A2CYP3A4CYP2C19LMNA | |
| SCHEMBL8059180 | 0.78 | GRM2 (0.45) | GPR52MAPT | |
| SCHEMBL8046498 | 0.78 | TBXAS1 (0.50) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A | |
| SCHEMBL8058443 | 0.77 | TBXAS1 (0.52) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A | |
| SCHEMBL8058494 | 0.76 | CYP2C19 (0.40) | SMN1; SMN2CYP2C19LMNARAB9ATDP1 | |
| SCHEMBL8058455 | 0.73 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A | |
| SCHEMBL7633968 | 0.73 | KIF11 (0.43) | HTTCYP1A2CYP2D6CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046180-A | NAALADase inhibitors | GUILFORD PHARMACEUTICALS INC. (US) | 2000-04-04 | — | — | US | disclosed |