SCHEMBL8046897

SCHEMBL8046897

Cc1ccc(S(=O)(=O)c2[c]ccc(S(=O)(=O)c3ccc(C)c(C)c3)c2)cc1C

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ALDH1A1 P00352 6/20 0.44
PKM P14618 2/20 0.44
GAA P10253 2/20 0.44
POLB P06746 2/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HTT P42858 1/20 0.38
KMT2A Q03164 2/20 0.38
TSHR P16473 2/20 0.36
ATM Q13315 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
MAPK1 P28482 1/20 0.34
RAPGEF4 Q8WZA2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8058723 0.84 GAA (0.57) TDP1ALDH1A1PKMGAAPOLB
SCHEMBL47890 0.81 LMNA (0.67) LMNATDP1ALDH1A1PKMGAA
SCHEMBL15460389 0.79 LMNA (0.64) LMNATDP1ALDH1A1PKMGAA
SCHEMBL8046870 0.79 GAA (0.50) LMNATDP1ALDH1A1GAAPOLB
SCHEMBL8059405 0.77 ALDH1A1 (0.57) LMNAALDH1A1PKMGAAPOLB
SCHEMBL8061637 0.77 KMT2A (0.42) LMNATDP1ALDH1A1PKMGAA
SCHEMBL8046992 0.77 HTR6 (0.54) LMNAALDH1A1GAAPOLBMAPT
SCHEMBL8059424 0.74 ALDH1A1 (0.47) LMNATDP1ALDH1A1GAAPOLB
SCHEMBL116485 0.74 GAA (0.70) LMNATDP1ALDH1A1PKMGAA
SCHEMBL15460390 0.74 GAA (0.70) LMNATDP1ALDH1A1PKMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed