Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933310 | 0.80 | HTR1A (0.38) | ALDH1A1LMNAKDM4EHSD17B10HTR1A | |
| SCHEMBL6932616 | 0.80 | KCNH2 (0.51) | ALDH1A1LMNAGAAKDM4EHSD17B10 | |
| SCHEMBL6932612 | 0.80 | KCNH2 (0.51) | ALDH1A1LMNAGAAKDM4EHSD17B10 | |
| SCHEMBL6930432 | 0.74 | ALDH1A1 (0.43) | ALDH1A1LMNAKDM4EHSD17B10MEN1 | |
| SCHEMBL6930424 | 0.74 | ALDH1A1 (0.43) | ALDH1A1LMNAKDM4EHSD17B10MEN1 | |
| SCHEMBL6930423 | 0.70 | HTR6 (0.43) | ALDH1A1LMNAKDM4EHSD17B10MEN1 | |
| SCHEMBL4830439 | 0.66 | KCNH2 (0.47) | ALDH1A1LMNAGAAKMT2AHTR1A | |
| SCHEMBL6820490 | 0.66 | TMEM97 (0.36) | ALDH1A1LMNAGAAKDM4EHSD17B10 | |
| SCHEMBL6816875 | 0.64 | DRD2 (0.35) | MEN1KMT2AADRA1AOPRM1HTR1A | |
| SCHEMBL8162682 | 0.64 | DRD2 (0.35) | MEN1KMT2AADRA1AOPRM1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025096-A1 | SUBSTITUTED CHROMAN DERIVATIVES | AstraZeneca AB (SE) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999014213-A1 | SUBSTITUTED CHROMAN DERIVATIVES | ASTRAZENECA AB (SE) | 1999-03-25 | — | — | WO | disclosed |