Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523266 | 0.81 | FAAH (0.41) | FAAHEPHX2 | |
| SCHEMBL27966414 | 0.80 | HSD11B1 (0.37) | PRMT5WDR77MEN1KMT2AFAAH | |
| SCHEMBL8064643 | 0.79 | MEN1 (0.50) | KDM1APRMT5WDR77MEN1KMT2A | |
| SCHEMBL27549150 | 0.75 | KDM1A (0.57) | KDM1APRMT5WDR77MEN1KMT2A | |
| SCHEMBL10467463 | 0.72 | KDM1A (0.53) | KDM1AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL12871712 | 0.70 | GRIN2B (0.52) | KDM1AMEN1KMT2AALDH1A1ADAM17 | |
| SCHEMBL8755394 | 0.68 | SLC6A3 (0.39) | KDM1AMEN1KMT2AMAPTSLC6A4 | |
| SCHEMBL29065708 | 0.67 | EPHX2 (0.47) | MEN1KMT2AFAAHCNR2EPHX2 | |
| SCHEMBL21383340 | 0.67 | SLC6A4 (0.54) | ALDH1A1SLC6A4SLC6A2SLC6A3SIGMAR1 | |
| SCHEMBL21002189 | 0.66 | KDM1A (0.49) | KDM1APRMT5WDR77MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000001450-A | SYNTHESIS OF INTERMEDIATE OF 1,2-DIOXETANES | TROPIX INC | 2000-01-07 | — | — | JP | disclosed |