Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 16/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066070 | 0.88 | HTT (0.57) | RXFP1HDAC7KMT2APOLB | |
| SCHEMBL15906093 | 0.86 | RXFP1 (0.60) | RXFP1RAB9AKMT2AMEN1POLB | |
| SCHEMBL8054760 | 0.84 | HDAC7 (0.55) | RXFP1HDAC7KMT2AMEN1POLB | |
| SCHEMBL3789304 | 0.82 | L3MBTL1 (0.56) | RXFP1RAB9AKMT2AMEN1POLB | |
| SCHEMBL8068535 | 0.80 | HDAC7 (0.49) | HDAC7KMT2AMEN1 | |
| SCHEMBL8066228 | 0.80 | HTT (0.48) | — | |
| SCHEMBL8071515 | 0.78 | HDAC7 (0.45) | HDAC7KMT2A | |
| SCHEMBL8053373 | 0.75 | POLB (0.46) | KMT2AMEN1POLB | |
| SCHEMBL8064800 | 0.75 | HTT (0.52) | KMT2AMEN1 | |
| SCHEMBL8033863 | 0.74 | GAA (0.57) | HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067600-A2 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |