Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065662 | 1.00 | CES2 (0.48) | CES2HSPB1MGLLCYP1A2PTPRC | |
| SCHEMBL8065659 | 0.90 | HSPB1 (0.48) | CES2HSPB1CYP1A2PTPRCBCHE | |
| SCHEMBL4756437 | 0.90 | HSPB1 (0.48) | CES2HSPB1CYP1A2PTPRCBCHE | |
| SCHEMBL1639309 | 0.85 | ALDH1A1 (0.53) | CYP1A2ALDH1A1HPGDMAPK1MAPT | |
| SCHEMBL2402136 | 0.81 | TTR (0.55) | CES2HSPB1CYP1A2ALDH1A1TP53 | |
| SCHEMBL2402141 | 0.81 | TTR (0.55) | CES2HSPB1CYP1A2ALDH1A1TP53 | |
| SCHEMBL8065636 | 0.80 | POLB (0.51) | CES2CES1PTGDR2ALDH1A1MAPK1 | |
| SCHEMBL8065631 | 0.80 | POLB (0.51) | CES2CES1PTGDR2ALDH1A1MAPK1 | |
| SCHEMBL8063663 | 0.79 | AKR1C3 (0.53) | PTPRCPTGDR2ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL8063665 | 0.79 | AKR1C3 (0.53) | PTPRCPTGDR2ALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012676-B2 | Processes for producing aryl carbamates, isocynates and polyureas using diaryl carbonate | GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (CN) | 2015-04-21 | — | — | US | disclosed |
| US-20130079542-A1 | PROCESSES FOR PRODUCING ARYL CARBAMATES, ISOCYNATES AND POLYUREAS USING DIARYL CARBONATE | NATIONAL CHUNG HSING UNIVERSITY (TW) | 2013-03-28 | — | — | US | disclosed |
| US-6143917-A | FROM A DIARYL CARBONATE AND AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATOM LOCATED AT AN N-POSITION UNDER MODERATE CONDITIONS AT A HIGH REACTION RATE WITH A HIGH SELECTIVITY AND WITH A HIGH YIELD | UBE INDUSTRIES, LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0902014-A1 | PROCESS FOR PRODUCING ARYL CARBAMATES | UBE INDUSTRIES LIMITED (JP) | 1999-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079542-A1 | PROCESSES FOR PRODUCING ARYL CARBAMATES, ISOCYNATES AND POLYUREAS USING DIARYL CARBONATE | UROD, DDC, TST | CES2 1518/4885HSPB1 2245/4885MGLL 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.