Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068374 | 0.88 | CHRM2 (0.41) | PDK1NPC1ALDH1A1GLAHTT | |
| SCHEMBL7107756 | 0.77 | TRPM8 (0.59) | LMNANPC1ALDH1A1GLAHTT | |
| SCHEMBL11552690 | 0.75 | NPC1 (0.50) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL14166018 | 0.72 | PDK1 (0.57) | PDK1MEN1LMNAMAPTKMT2A | |
| SCHEMBL7109134 | 0.71 | KDM4E (0.44) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL1925076 | 0.70 | ALDH1A1 (0.59) | MEN1LMNAMAPTKMT2ANPC1 | |
| Bromide SCHEMBL5435104 | 0.69 | PDK1 (0.51) | PDK1MEN1LMNAMAPTKMT2A | |
| SCHEMBL7107759 | 0.69 | MMP1 (0.47) | MEN1LMNAMAPTKMT2ATRPM8 | |
| SCHEMBL25920400 | 0.69 | RAB9A (0.53) | MEN1MAPTKMT2ANPC1ALDH1A1 | |
| SCHEMBL25920399 | 0.69 | CHRM2 (0.43) | PDK1MAPTNPC1ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013639-A1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-28 | — | — | EP | disclosed |