Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.35 |
| ▸ | BMP1 | P13497 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8073480 | 0.91 | DRD2 (0.38) | DRD2DRD3HRH3THRATHRB | |
| SCHEMBL8059397 | 0.90 | THRA (0.42) | DRD2DRD3HRH3THRATHRB | |
| SCHEMBL8059495 | 0.89 | THRA (0.41) | DRD2DRD3HRH3THRATHRB | |
| SCHEMBL8059455 | 0.86 | HRH3 (0.40) | DRD2DRD3HRH3THRATHRB | |
| SCHEMBL8075018 | 0.83 | SLC6A2 (0.43) | DRD2DRD3HRH3THRATHRB | |
| SCHEMBL8444225 | 0.82 | TSHR (0.40) | DRD2DRD3HRH3THRATHRB | |
| SCHEMBL8059406 | 0.82 | SLC9A1 (0.47) | — | |
| SCHEMBL8068481 | 0.81 | THRA (0.43) | DRD2DRD3HRH3THRATHRB | |
| SCHEMBL8075422 | 0.81 | PKM (0.48) | THRATHRBPOLBPKM | |
| Hydrochloric Acid SCHEMBL8070153 | 0.80 | PKM (0.47) | THRATHRBPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |