Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.51 |
| ▸ | CCR2 | P41597 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073771 | 0.91 | KMT2A (0.58) | KMT2AMEN1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL8444778 | 0.88 | SLC9A1 (0.50) | SIGMAR1CCR2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8068489 | 0.87 | SLC9A1 (0.49) | SIGMAR1CCR2KMT2AMEN1 | |
| SCHEMBL8444776 | 0.87 | SIGMAR1 (0.46) | SIGMAR1CCR2KMT2AMEN1PARP1 | |
| Hydrochloric Acid SCHEMBL8068487 | 0.86 | SIGMAR1 (0.45) | SIGMAR1CCR2KMT2AMEN1PARP1 | |
| SCHEMBL8059678 | 0.82 | NPSR1 (0.44) | KMT2APOLBTP53L3MBTL1LMNA | |
| Piperidine SCHEMBL8068938 | 0.80 | TSHR (0.42) | CCR2KMT2APOLBL3MBTL1LMNA | |
| SCHEMBL8068849 | 0.80 | ALDH1A1 (0.54) | SIGMAR1KMT2APOLBMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8077076 | 0.79 | KMT2A (0.52) | KMT2AMEN1POLBMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8077073 | 0.78 | KMT2A (0.51) | KMT2AMEN1POLBMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |