Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.46 |
| ▸ | CCR2 | P41597 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8068487 | 0.99 | SIGMAR1 (0.45) | SIGMAR1CCR2KMT2AMEN1PARP1 | |
| Hydrochloric Acid SCHEMBL8077073 | 0.91 | KMT2A (0.51) | KMT2AMEN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8068934 | 0.87 | SIGMAR1 (0.51) | SIGMAR1CCR2KMT2AMEN1PARP1 | |
| SCHEMBL8444778 | 0.86 | SLC9A1 (0.50) | SIGMAR1CCR2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8068489 | 0.85 | SLC9A1 (0.49) | SIGMAR1CCR2KMT2AMEN1 | |
| SCHEMBL8444243 | 0.82 | ALDH1A1 (0.53) | SIGMAR1KMT2AUSP2ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8070683 | 0.81 | ALDH1A1 (0.52) | SIGMAR1KMT2AUSP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8446065 | 0.80 | CYP19A1 (0.50) | KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8446233 | 0.80 | MAPT (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8068683 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723956-B1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AG (DE) | 1999-10-13 | — | — | EP | claimed |