Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.44 |
| ▸ | GHSR | Q92847 | 3/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | CASP4 | P49662 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP9 | P55211 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053617 | 0.80 | RAB9A (0.44) | RAB9A | |
| SCHEMBL4542819 | 0.79 | RAB9A (0.54) | RAB9A | |
| SCHEMBL4537242 | 0.77 | NPC1 (0.53) | BDKRB1RAB9A | |
| SCHEMBL8062877 | 0.77 | ALDH1A1 (0.50) | — | |
| SCHEMBL8066636 | 0.75 | RAB9A (0.46) | RAB9A | |
| SCHEMBL8068354 | 0.75 | PSEN1 (0.47) | BDKRB1 | |
| SCHEMBL4541024 | 0.74 | RAB9A (0.48) | BDKRB1RAB9A | |
| SCHEMBL4542153 | 0.74 | ALDH1A1 (0.47) | RAB9A | |
| SCHEMBL4542928 | 0.74 | LMNA (0.55) | BDKRB1CASP1 | |
| SCHEMBL8062528 | 0.73 | RAB9A (0.50) | MMP2MMP9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |