Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 5/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059720 | 0.89 | THRA (0.41) | SMN1; SMN2BMP1LMNAPOLBHRH3 | |
| SCHEMBL8074945 | 0.84 | F10 (0.35) | CYP2C19SMN1; SMN2BMP1LMNAHRH3 | |
| SCHEMBL8068481 | 0.82 | THRA (0.43) | CYP1A2TSHRCYP2C19SMN1; SMN2BMP1 | |
| SCHEMBL8068838 | 0.79 | ALDH1A1 (0.41) | TSHRBMP1LMNAHRH3ALDH1A1 | |
| SCHEMBL8068832 | 0.74 | PKM (0.43) | CYP1A2TSHRCYP2C19SMN1; SMN2BMP1 | |
| SCHEMBL8073466 | 0.74 | BMP1 (0.40) | BMP1HRH3 | |
| SCHEMBL8075422 | 0.73 | PKM (0.48) | POLB | |
| Hydrochloric Acid SCHEMBL8070153 | 0.72 | PKM (0.47) | POLB | |
| SCHEMBL15329199 | 0.71 | CYP4A11 (0.62) | CYP1A2TSHRCYP2C19SMN1; SMN2MAPT | |
| SCHEMBL283181 | 0.70 | CA1 (0.58) | POLBMAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |