Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25434899 | 0.75 | GAA (0.51) | ALDH1A1CNR1GAAKMT2AMEN1 | |
| SCHEMBL9700311 | 0.75 | GAA (0.51) | ALDH1A1CNR1GAAKMT2AMEN1 | |
| SCHEMBL8554573 | 0.72 | MTNR1A (0.41) | TSHRGAASMN1; SMN2 | |
| SCHEMBL15701677 | 0.71 | SIGMAR1 (0.65) | HTR2AHRH1HTR2CHTR1AADRA2A | |
| SCHEMBL10816361 | 0.69 | CHRM2 (0.44) | ALDH1A1KMT2AMEN1HTR1A | |
| SCHEMBL8061014 | 0.68 | GAA (0.59) | HTR2AHRH1ALDH1A1HTR2CGAA | |
| SCHEMBL8553144 | 0.68 | CHRM2 (0.43) | ALDH1A1 | |
| SCHEMBL9700324 | 0.68 | ADRA2A (0.47) | HTR2AHRH1HTR2CGAAHTR1A | |
| SCHEMBL29512776 | 0.68 | KEAP1 (0.40) | HTR2AHRH1ALDH1A1KDM1AGAA | |
| SCHEMBL20957032 | 0.67 | ALDH1A1 (0.73) | ALDH1A1KDM1AKMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013648-A | IMMUNOMODULATORS | SANOFI (FR) | 2000-01-11 | — | — | US | disclosed |
| EP-0833818-A1 | CB 2? RECEPTOR AGONIST COMPOUNDS | SANOFI (FR) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000860-A1 | CB2 RECEPTOR AGONIST COMPOUNDS | SANOFI (FR) | 1997-01-09 | — | — | WO | disclosed |