Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | EDNRA | P25101 | 3/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8066341 | 0.90 | ALDH1A1 (0.46) | TSHRGAAALDH1A1PTGESALOX5 | |
| SCHEMBL8470011 | 0.89 | ALDH1A1 (0.44) | TSHRGAAALDH1A1EDNRAPTGES | |
| SCHEMBL8074297 | 0.87 | TSHR (0.40) | TSHRGAAALDH1A1PTGESALOX5 | |
| SCHEMBL9407911 | 0.85 | LMNA (0.49) | GAAALDH1A1LMNASMN1; SMN2KEAP1 | |
| SCHEMBL8076269 | 0.83 | ALDH1A1 (0.42) | TSHRGAAALDH1A1PTGESLMNA | |
| SCHEMBL8592383 | 0.78 | ALDH1A1 (0.43) | TSHRGAAALDH1A1EDNRAPTGES | |
| SCHEMBL8076560 | 0.78 | MMP3 (0.42) | TSHRALDH1A1PTGESLMNAKEAP1 | |
| SCHEMBL9407919 | 0.78 | LMNA (0.43) | GAAALDH1A1LMNASMN1; SMN2NPSR1 | |
| Bromide SCHEMBL8469737 | 0.77 | ALDH1A1 (0.50) | TSHRGAAALDH1A1PTGESALOX5 | |
| SCHEMBL8076290 | 0.77 | KEAP1 (0.40) | LMNAKEAP1NFE2L2TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330050-B1 | Special chemiluminescent acridine derivatives and their use in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 2000-08-23 | — | — | EP | disclosed |
| EP-0602524-A1 | Chemiluminescence marked sequences and their use in sequence testing | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-22 | — | — | EP | disclosed |
| EP-0330050-A2 | Special chemiluminescent acridine derivatives and their use in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-30 | — | — | EP | disclosed |