Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 4/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9407961 | 0.88 | PTGES (0.40) | L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL8076269 | 0.84 | ALDH1A1 (0.42) | LMNAKDM4ETOP2ATOP2BALDH1A1 | |
| SCHEMBL9407911 | 0.84 | LMNA (0.49) | LMNAKDM4ESMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL8076290 | 0.81 | KEAP1 (0.40) | LMNAKDM4ETOP2ATOP2BTP53 | |
| SCHEMBL8076560 | 0.79 | MMP3 (0.42) | LMNATOP2ATOP2BALDH1A1KMT2A | |
| SCHEMBL8076250 | 0.78 | TSHR (0.42) | LMNAKDM4ESMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL7462218 | 0.76 | TOP2A (0.41) | LMNAKDM4ESMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL8469225 | 0.75 | ALDH1A1 (0.48) | LMNAKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL8469659 | 0.75 | LMNA (0.51) | LMNAKDM4ESMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL8080887 | 0.75 | LMNA (0.44) | LMNAKDM4ESMN1; SMN2MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602524-A1 | Chemiluminescence marked sequences and their use in sequence testing | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-22 | — | — | EP | disclosed |