Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 7/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2370319 | 0.89 | LMNA (0.42) | LMNAL3MBTL1TP53MAPTRXFP1 | |
| SCHEMBL2370127 | 0.81 | NPC1 (0.44) | LMNAL3MBTL1TP53MAPTRXFP1 | |
| SCHEMBL2370368 | 0.71 | ITK (0.47) | LMNATP53MAPTRXFP1LCK | |
| SCHEMBL2370365 | 0.71 | ITK (0.47) | LMNATP53MAPTRXFP1LCK | |
| SCHEMBL798853 | 0.71 | LMNA (0.62) | LMNAL3MBTL1POLB | |
| SCHEMBL2371227 | 0.71 | APP (0.37) | LMNATP53MAPTRXFP1LCK | |
| SCHEMBL2371233 | 0.70 | HTT (0.45) | MAPTRXFP1LCK | |
| SCHEMBL2369950 | 0.69 | RAB9A (0.41) | LMNATP53MAPTRXFP1LCK | |
| SCHEMBL2370208 | 0.69 | ALDH1A1 (0.44) | MAPTRXFP1LCK | |
| SCHEMBL807916 | 0.69 | DPP4 (0.37) | TP53MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035055-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-22 | — | — | WO | disclosed |