Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 7/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10286916 | 0.95 | ALDH1A1 (0.38) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL808022 | 0.88 | LMNA (0.35) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10286918 | 0.87 | GAA (0.39) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL808223 | 0.87 | LMNA (0.43) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL808048 | 0.87 | LMNA (0.36) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10286917 | 0.84 | GRM5 (0.41) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL807935 | 0.83 | SMN1; SMN2 (0.41) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL807956 | 0.83 | PRCP (0.35) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10287788 | 0.80 | LMNA (0.38) | GAAALDH1A1MAPTCYP2C9LMNA | |
| SCHEMBL808032 | 0.75 | DHFR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |