Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.36 |
| ▸ | TUBB | P07437 | 4/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807956 | 0.86 | PRCP (0.35) | ALDH1A1EPHX2TUBB4ATUBBTUBA3C | |
| SCHEMBL10286916 | 0.86 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1EPHX2LMNATSHR | |
| SCHEMBL808223 | 0.84 | LMNA (0.43) | SMN1; SMN2ALDH1A1LMNATSHRTUBB4A | |
| SCHEMBL10286918 | 0.84 | GAA (0.39) | SMN1; SMN2ALDH1A1EPHX2LMNATSHR | |
| SCHEMBL808048 | 0.84 | LMNA (0.36) | SMN1; SMN2ALDH1A1EPHX2LMNATSHR | |
| SCHEMBL808022 | 0.79 | LMNA (0.35) | SMN1; SMN2ALDH1A1LMNATSHRCYP2C9 | |
| SCHEMBL808032 | 0.77 | DHFR (0.34) | — | |
| SCHEMBL808024 | 0.73 | TSHR (0.37) | SMN1; SMN2LMNATSHRMAPT | |
| SCHEMBL807920 | 0.72 | SIGMAR1 (0.33) | — | |
| SCHEMBL808232 | 0.71 | CNR2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |