Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083584 | 0.87 | RIPK1 (0.42) | RIPK1TLR2MMP8CTSKOPRK1 | |
| SCHEMBL8083527 | 0.87 | RIPK1 (0.40) | RIPK1TLR2MMP8CTSKOPRK1 | |
| SCHEMBL8095253 | 0.75 | RIPK1 (0.39) | RIPK1MMP8CTSKOPRK1MAPT | |
| SCHEMBL8095188 | 0.74 | MMP8 (0.39) | MMP8MAPTL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL8090156 | 0.74 | MMP8 (0.39) | MMP8MAPTL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL8091670 | 0.73 | MMP8 (0.38) | MMP8MAPTL3MBTL1 | |
| SCHEMBL10937862 | 0.70 | RIPK1 (0.64) | RIPK1MMP8OPRK1MAPTL3MBTL1 | |
| SCHEMBL7438658 | 0.70 | RIPK1 (0.68) | RIPK1MMP8OPRK1MAPTL3MBTL1 | |
| SCHEMBL8095236 | 0.67 | RIPK1 (0.52) | RIPK1TLR2MMP8OPRK1MAPT | |
| SCHEMBL8095305 | 0.67 | CYP3A4 (0.35) | MMP8CTSKOPRK1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |