Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091511 | 0.91 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1HSD17B1HSD11B1CA12 | |
| SCHEMBL8098063 | 0.86 | CES2 (0.37) | ALDH1A1POLBLMNA | |
| SCHEMBL8098096 | 0.78 | CES2 (0.35) | SMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL8083627 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1HSD17B1HSD11B1CA12 | |
| SCHEMBL7443096 | 0.68 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1CA1CA2CA9 | |
| SCHEMBL8083569 | 0.67 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL8083534 | 0.67 | CA12 (0.52) | SMN1; SMN2ALDH1A1HSD17B1HSD11B1CA12 | |
| SCHEMBL8083579 | 0.66 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL8098083 | 0.66 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1HSD17B1HSD11B1CA12 | |
| SCHEMBL8098230 | 0.66 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1HSD17B1HSD11B1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |