Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL11662874 | 0.95 | SRC (0.44) | SRCL3MBTL1TDP1LTA4HTSHR | |
| SCHEMBL2818993 | 0.95 | SRC (0.44) | SRCL3MBTL1TDP1LTA4HTSHR | |
| SCHEMBL9851832 | 0.95 | SRC (0.44) | SRCL3MBTL1TDP1LTA4HTSHR | |
| SCHEMBL5161238 | 0.95 | SRC (0.44) | SRCL3MBTL1TDP1LTA4HTSHR | |
| Zinc Ion SCHEMBL731771 | 0.95 | SRC (0.44) | SRCL3MBTL1TDP1LTA4HTSHR | |
| SCHEMBL10824057 | 0.91 | SRC (0.46) | SRCL3MBTL1TDP1LTA4HTSHR | |
| SCHEMBL11661895 | 0.77 | SRC (0.46) | SRCL3MBTL1TDP1LTA4HTSHR | |
| SCHEMBL11663521 | 0.76 | MEN1 (0.48) | L3MBTL1LTA4HMEN1KMT2AHTT | |
| SCHEMBL11657700 | 0.76 | CYP3A4 (0.52) | TDP1TSHRMEN1KMT2ALMNA | |
| SCHEMBL11662056 | 0.76 | MAPT (0.37) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514649-B1 | Stabilization of aqueous solutions of watersoluble polymers in the presence of hydroxylamine | CYTEC TECH CORP (US) | 2000-10-25 | — | — | EP | disclosed |
| EP-0514649-A1 | Stabilization of aqueous polymers in the presence of hydroxylamine | CYTEC TECHNOLOGY CORP. (US) | 1992-11-25 | — | — | EP | disclosed |
| US-4502972-A | ETHYLENE-PROPYLENE-DIENE TERPOLYMER | ETHYL CORPORATION (US) | 1985-03-05 | — | — | US | disclosed |
| US-4099954-A | Amide phosphorothiolate herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-07-11 | — | — | US | disclosed |