Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | MAX | P61244 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088847 | 0.82 | MYC (0.38) | CFTRVCAM1MEN1KMT2ARXFP1 | |
| SCHEMBL7268034 | 0.81 | ALOX5 (0.40) | CFTRMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7277069 | 0.80 | PDE4A (0.39) | VCAM1LMNAHTTMAPTPOLB | |
| SCHEMBL10695615 | 0.76 | MAPT (0.40) | MEN1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL7299515 | 0.76 | KDM4E (0.33) | KMT2AMAPTPOLBGAAALDH1A1 | |
| SCHEMBL8088445 | 0.75 | ADORA3 (0.41) | MEN1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL8085141 | 0.75 | RECQL (0.44) | LMNASMN1; SMN2HTTMAPTPOLB | |
| SCHEMBL7291289 | 0.75 | CCNC (0.34) | KMT2ALMNAHTTMAPTPOLB | |
| SCHEMBL10697020 | 0.75 | ALDH1A1 (0.36) | MEN1KMT2ASMN1; SMN2HTTHPGD | |
| SCHEMBL8088352 | 0.75 | KDM4E (0.37) | MEN1KMT2AMYCMAXSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |