Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | PRNP | P04156 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084839 | 0.78 | AOC3 (0.34) | HTR2CHTR2BBCHEABCB1 | |
| SCHEMBL8088287 | 0.76 | CYP17A1 (0.46) | HTR2CHTR2BRAB9AKMT2A | |
| SCHEMBL8084817 | 0.73 | HTR2C (0.43) | HTR2CHTR2BALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8084767 | 0.67 | RAB9A (0.50) | HTR2CHTR2BALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8084810 | 0.65 | CHEK2 (0.46) | LTA4HLMNASMN1; SMN2BCHE | |
| SCHEMBL22303101 | 0.65 | RXFP1 (0.52) | HTTPRNPALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8076715 | 0.65 | ALDH1A1 (0.32) | ALDH1A1RAB9AABCB1MAPTKMT2A | |
| SCHEMBL24827561 | 0.64 | ALDH1A1 (0.60) | HTTALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL13601938 | 0.64 | HTR1A (0.43) | MAPT | |
| SCHEMBL14641227 | 0.62 | HTR1A (0.46) | HTTPRNPSMN1; SMN2RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |