SCHEMBL8084839

SCHEMBL8084839

CC(C)CN(C)CCN(C)c1ccc(CCSc2ccnc3ccccc23)cc1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.34
ABCB1 P08183 1/20 0.33
ROCK1 Q13464 1/20 0.33
GBA1 P04062 2/20 0.32
HRH3 Q9Y5N1 2/20 0.32
KDM4C Q9H3R0 1/20 0.32
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
NUDT1 P36639 1/20 0.30
BCHE P06276 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8084817 0.81 HTR2C (0.43) ABCB1HTR2CHTR2B
SCHEMBL8084808 0.78 HTR2C (0.39) ABCB1HTR2CHTR2BBCHE
SCHEMBL8084734 0.69 HTR2C (0.44) HTR2CHTR2B
SCHEMBL8084810 0.69 CHEK2 (0.46) HRH3BCHE
SCHEMBL8076715 0.66 ALDH1A1 (0.32) ABCB1
SCHEMBL13416698 0.66 AOC3 (0.65) AOC3
SCHEMBL13601938 0.65 HTR1A (0.43) HRH3
SCHEMBL2333890 0.65 HTR1A (0.47)
SCHEMBL8908139 0.65 HTR1A (0.47)
SCHEMBL12796611 0.64 LOXL2 (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6057447-A BACTERICIDES FOR CAMPYLOBACTER ZENYAKU KOGYO KABUSHIKI KAISHA (JP) 2000-05-02 US disclosed
EP-0926139-A1 QUINOLINE SULFIDE DERIVATIVES ZENYAKU KOGYO KABUSHIKIKAISHA (JP) 1999-06-30 EP disclosed