Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 6/20 | 0.34 |
| ▸ | DRD1 | P21728 | 6/20 | 0.34 |
| ▸ | DRD5 | P21918 | 6/20 | 0.34 |
| ▸ | DRD3 | P35462 | 6/20 | 0.34 |
| ▸ | DRD4 | P21917 | 5/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391964 | 0.84 | ACHE (0.38) | MAPTLMNACYP1A1CYP1A2CYP1B1 | |
| SCHEMBL6536500 | 0.81 | ATM (0.34) | LMNAALDH1A1OPRM1OPRL1 | |
| SCHEMBL9546931 | 0.74 | MAOA (0.36) | LMNARAB9AKMT2A | |
| SCHEMBL7972739 | 0.73 | MAPT (0.43) | MAPTALDH1A1RAB9ADRD2DRD4 | |
| SCHEMBL6861332 | 0.73 | DRD1 (0.34) | MAPTLMNADRD2DRD1DRD5 | |
| SCHEMBL6536705 | 0.71 | DRD1 (0.33) | MAPTLMNAALDH1A1DRD2DRD1 | |
| SCHEMBL7455420 | 0.71 | ACHE (0.37) | ALDH1A1OPRM1OPRL1 | |
| SCHEMBL6536567 | 0.69 | PARP1 (0.34) | CA1CA2 | |
| SCHEMBL6689248 | 0.68 | HDAC9 (0.33) | ALDH1A1KMT2AOPRM1 | |
| SCHEMBL7764690 | 0.67 | MEN1 (0.37) | MAPTLMNACYP1A2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995010790-A1 | HIGH REFRACTIVE INDEX PHOTOCHROMIC OPHTHALMIC ARTICLE | PPG INDUSTRIES, INC. (US) | 1995-04-20 | — | — | WO | claimed |