SCHEMBL8089330

SCHEMBL8089330

COC(=O)CC1(CC(=O)Cc2c(C)cc(C)cc2C)CCCC(C)C1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.47
EPHX2 P34913 2/20 0.34
GAA P10253 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TAS1R3 Q7RTX0 4/20 0.32
TAS1R1 Q7RTX1 4/20 0.32
TAS1R2 Q8TE23 4/20 0.32
HRH3 Q9Y5N1 2/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8096827 0.88 THRB (0.32) EPHX2GAANPSR1KDM4ETAS1R3
SCHEMBL8094213 0.86 KMT2A (0.38) EPHX2GAANPSR1ALDH1A1KDM4E
SCHEMBL8090778 0.86 TAS1R3 (0.32) CYP1A2TAS1R3TAS1R1TAS1R2
SCHEMBL8094128 0.85 CYP1A2 (0.44) CYP1A2ALDH1A1RAB9A
SCHEMBL8089218 0.85 KMT2A (0.37) EPHX2GAANPSR1ALDH1A1TAS1R3
SCHEMBL8089298 0.85 KMT2A (0.37) EPHX2GAANPSR1ALDH1A1TAS1R3
SCHEMBL8089426 0.81 DPP4 (0.32) EPHX2
SCHEMBL8089299 0.80 P2RX7 (0.32) EPHX2
SCHEMBL8090780 0.79 MMP1 (0.32)
SCHEMBL8090997 0.79 P2RX3 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6150304-A HERBICIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2000-11-21 US disclosed
US-5840661-A HERBICIDES OR INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-11-24 US disclosed