Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448384 | 0.89 | MMP8 (0.37) | MMP2LMNA | |
| SCHEMBL7437102 | 0.88 | CA2 (0.33) | ALDH1A1CA1CA2CA12MMP2 | |
| SCHEMBL7445682 | 0.87 | ITGB1 (0.31) | ITGB1ITGA4 | |
| SCHEMBL7433114 | 0.86 | TBXA2R (0.30) | TBXA2R | |
| SCHEMBL7433244 | 0.84 | F2 (0.34) | CA2F2TPSAB1ITGB1ITGA4 | |
| SCHEMBL7442402 | 0.83 | AKR1C3 (0.39) | ALDH1A1CA1CA2CA9LMNA | |
| SCHEMBL7444716 | 0.82 | MME (0.37) | ITGB1ITGA4 | |
| SCHEMBL7433865 | 0.81 | ITGB1 (0.31) | ALDH1A1ITGB1ITGA4 | |
| SCHEMBL7443545 | 0.80 | ALDH1A1 (0.42) | ALDH1A1HDAC3HDAC1PKM | |
| SCHEMBL7429926 | 0.79 | CA12 (0.33) | CA1CA2CA12CA9F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814622-A | COMPOUND USEFUL AS TRYPSIN LIKE SERINE PROTEASE AS THROMBIN INHIBITORS | ADIR ET COMPAGNIE (FR) | 1998-09-29 | — | — | US | disclosed |