Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628069 | 0.86 | NPC1 (0.61) | DYRK1ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5950603 | 0.84 | NPC1 (0.59) | DYRK1ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL2033015 | 0.83 | ASIC3 (0.43) | ASIC3DYRK1ANPC1RAB9AALDH1A1 | |
| SCHEMBL27760768 | 0.81 | RAB9A (0.64) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29992900 | 0.81 | RAB9A (0.64) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28342829 | 0.79 | ACHE (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL2614971 | 0.79 | MAPK14 (0.60) | NPC1RAB9AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL18255986 | 0.79 | NPC1 (0.54) | DYRK1ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL20390781 | 0.79 | ASIC3 (0.67) | ASIC3NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL29651489 | 0.79 | ASIC3 (0.67) | ASIC3NPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229911-A1 | New pharmaceutical combinations for NOS inhibitors | PFIZER INC | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229911-A1 | New pharmaceutical combinations for NOS inhibitors | NOS1, NOS3, NPBWR1 | ASIC3 1659/4885DYRK1A 1498/4885NPC1 1438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.