Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 8/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13925023 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL21853279 | 0.90 | CTSK (0.44) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL8245145 | 0.90 | CTSK (0.44) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL26098935 | 0.89 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL13067403 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP2C9ALDH1A1MAPTKMT2A | |
| SCHEMBL330005 | 0.85 | CTSK (0.46) | SMN1; SMN2CTSKCTSSALDH1A1HDAC4 | |
| SCHEMBL1937079 | 0.85 | CTSK (0.46) | SMN1; SMN2CTSKCTSSALDH1A1HDAC4 | |
| SCHEMBL3683654 | 0.85 | CTSK (0.46) | SMN1; SMN2CTSKCTSSALDH1A1HDAC4 | |
| SCHEMBL330004 | 0.85 | CTSK (0.46) | SMN1; SMN2CTSKCTSSALDH1A1HDAC4 | |
| SCHEMBL1937084 | 0.85 | CTSK (0.46) | SMN1; SMN2CTSKCTSSALDH1A1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12023661-B2 | Nitrogen heterocyclic carbene ligands and ruthenium catalysts thereof, preparation method therefor and application thereof | Paimai New Materials (chengdu) Co., Ltd. (CN) | 2024-07-02 | — | — | US | disclosed |
| US-20220161246-A1 | NITROGEN HETEROCYCLIC CARBENE LIGANDS AND RUTHENIUM CATALYSTS THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Paimai New Materials (chengdu) Co., Ltd. (CN) | 2022-05-26 | — | — | US | disclosed |
| WO-2020140441-A1 | NITROGEN HETEROCYCLIC CARBENE LIGANDS AND RUTHENIUM CATALYSTS THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 成都开美思商务信息咨询中心(有限合伙) | 2020-07-09 | — | — | WO | disclosed |
| US-20090036708-A1 | Novel Process for the Preparation of Nonracemic Long Chain alpha-Amino Acid Derivatives | WUXI PHARMATECH CO., LTD. (CN) | 2009-02-05 | — | — | US | disclosed |
| US-20080286233-A1 | PIPERIZINYL MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2008-11-20 | — | — | US | disclosed |
| US-20070249637-A1 | Inhibitors Of Hepatitis C Virus Protease, And Compositions And Treatments Using The Same | COLLINS MICHAEL R | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220161246-A1 | NITROGEN HETEROCYCLIC CARBENE LIGANDS AND RUTHENIUM CATALYSTS THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | WEE2, WEE1, FARSB | SMN1; SMN2 4008/4885CYP1A2 355/4885CYP2C9 350/4885 |
| US-20090036708-A1 | Novel Process for the Preparation of Nonracemic Long Chain alpha-Amino Acid Derivatives | AADAT, BCAT1, BCAT2 | SMN1; SMN2 3463/4885CYP1A2 1381/4885CYP2C9 1298/4885 |
| US-20070249637-A1 | Inhibitors Of Hepatitis C Virus Protease, And Compositions And Treatments Using The Same | SERPINB1, CTSC, CTSV | SMN1; SMN2 4566/4885CYP1A2 278/4885CYP2C9 282/4885 |
| US-12023661-B2 | Nitrogen heterocyclic carbene ligands and ruthenium catalysts thereof, preparation method therefor and application thereof | WEE2, WEE1, FARSB | SMN1; SMN2 4008/4885CYP1A2 355/4885CYP2C9 350/4885 |
| US-20080286233-A1 | PIPERIZINYL MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | PRSS1, HPN, PREP | SMN1; SMN2 3652/4885CYP1A2 673/4885CYP2C9 1066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.