Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089547 | 0.86 | TSHR (0.33) | MAPT | |
| SCHEMBL10733179 | 0.83 | SLC6A2 (0.46) | MAPTADAM17SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8098980 | 0.81 | — | — | |
| SCHEMBL8099358 | 0.80 | ALDH1A1 (0.46) | MAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8090604 | 0.80 | KAT2B (0.49) | MAPT | |
| SCHEMBL8097654 | 0.77 | ALOX15 (0.43) | MAPT | |
| SCHEMBL8098966 | 0.76 | ADRB1 (0.36) | — | |
| SCHEMBL8103236 | 0.73 | NOTUM (0.43) | — | |
| SCHEMBL8099397 | 0.72 | MAPT (0.59) | MAPT | |
| SCHEMBL8089631 | 0.72 | P2RX7 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |