Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097781 | 0.86 | ADRA2A (0.43) | NLRP3NOTUMCA12CA1CA2 | |
| SCHEMBL8097604 | 0.86 | ADRA2A (0.43) | NLRP3NOTUMCA12CA1CA2 | |
| SCHEMBL8097787 | 0.85 | TSHR (0.40) | ALDH1A1SMN1; SMN2MAPTHSD17B10ALOX15 | |
| SCHEMBL8091366 | 0.81 | NOTUM (0.43) | NOTUML3MBTL1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL8099968 | 0.73 | MCHR1 (0.42) | NLRP3L3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8092415 | 0.73 | BRD4 (0.39) | NLRP3L3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8092437 | 0.71 | ADRA2A (0.43) | NLRP3MAPTHTTHPGDMEN1 | |
| SCHEMBL11656819 | 0.71 | GABRP (0.42) | NOTUML3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10930335 | 0.71 | NOTUM (0.44) | NOTUMALDH1A1SMN1; SMN2HSD17B10PKM | |
| SCHEMBL9181008 | 0.70 | ALDH1A1 (0.47) | NLRP3ALDH1A1SMN1; SMN2PKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1183907-C | Imidazoline compound, preparing process thereof and pharmaceutical composition contg. same | SERVIER LAB (FR) | 2005-01-12 | — | — | CN | disclosed |
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |