SCHEMBL8097869

SCHEMBL8097869

CCOc1nc(F)cc2nc(S(=O)(=O)Nc3c(Br)cnn3C)nn12

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6999983 0.78 TSHR (0.36)
SCHEMBL9176758 0.77 CCR4 (0.42) LMNA
Diclosulam SCHEMBL116344 0.76 GNRHR (0.35) LMNA
SCHEMBL6998020 0.75 GNRHR (0.32)
SCHEMBL9176684 0.75 ALDH1A1 (0.38)
SCHEMBL8107436 0.74 ALDH1A1 (0.32)
SCHEMBL8848572 0.74 GNRHR (0.34)
SCHEMBL8848901 0.73 LMNA (0.34) LMNA
SCHEMBL8848603 0.72 WDR5 (0.42) LMNA
SCHEMBL8418196 0.71 FABP4 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0537423-B1 N-pyrazolyl-1,2,4-triazolo(1,5-c)pyrimidine-2-sulfonamide herbicides DOWELANCO (US) 1997-10-08 EP claimed
EP-0537423-A1 N-pyrazolyl-1,2,4-triazolo(1,5-c)pyrimidine-2-sulfonamide herbicides DowElanco (US) 1993-04-21 EP claimed
US-5201938-A N-pyrazolyl-1,2,4-triazolo[1,5-c]pyrimidine-2-sulfonamide herbicides DOWELANCO (US) 1993-04-13 US claimed
US-6114580-A N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds DOW AGROSCIENCES LLC (US) 2000-09-05 US disclosed
EP-0888297-B1 N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS DOW AGROSCIENCES LLC (US) 2000-08-30 EP disclosed
US-5973148-A N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds DOW AGROSCIENCES LLC (US) 1999-10-26 US disclosed
EP-0537423-B1 N-pyrazolyl-1,2,4-triazolo(1,5-c)pyrimidine-2-sulfonamide herbicides DOWELANCO (US) 1997-10-08 EP disclosed
EP-0537423-A1 N-pyrazolyl-1,2,4-triazolo(1,5-c)pyrimidine-2-sulfonamide herbicides DowElanco (US) 1993-04-21 EP disclosed
US-5201938-A N-pyrazolyl-1,2,4-triazolo[1,5-c]pyrimidine-2-sulfonamide herbicides DOWELANCO (US) 1993-04-13 US disclosed