Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998020 | 0.88 | GNRHR (0.32) | ALDH1A1KDM4EPOLBMAPTHPGD | |
| SCHEMBL8848603 | 0.75 | WDR5 (0.42) | ALDH1A1MAPT | |
| SCHEMBL19756387 | 0.74 | RIPK2 (0.30) | RIPK2 | |
| SCHEMBL29396759 | 0.74 | WDR5 (0.39) | ALDH1A1 | |
| SCHEMBL8559900 | 0.73 | PDE4D (0.33) | MAPTRIPK2 | |
| SCHEMBL8015385 | 0.73 | L3MBTL1 (0.34) | ALDH1A1KDM4EPOLBMAPTHPGD | |
| SCHEMBL9176758 | 0.73 | CCR4 (0.42) | ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL18643336 | 0.72 | CA2 (0.40) | ALDH1A1KDM4EMAPTNPSR1 | |
| SCHEMBL8030891 | 0.72 | TRPV4 (0.30) | — | |
| SCHEMBL9176684 | 0.72 | ALDH1A1 (0.38) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114580-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0888297-B1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-08-30 | — | — | EP | disclosed |
| US-5973148-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 1999-10-26 | — | — | US | disclosed |